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ARHGAP25 Inhibits Pancreatic Adenocarcinoma Growth by Suppressing Glycolysis via AKT/mTOR Pathway

Increasing evidence reveals that the Rho GTPase-activating protein is a crucial negative regulator of Rho family GTPase involved in tumorigenesis. The Rho GTPase-activating protein 25 (ARHGAP25) has been shown to specifically inactivate the Rho family GTPase Rac1, which plays an important role in pa...

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Detalles Bibliográficos
Autores principales: Huang, Wen-Kuan, Chen, Yi, Su, Huafang, Chen, Tung-Ying, Gao, Jiwei, Liu, Yaxuan, Yeh, Chun-Nan, Li, Shuijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120455/
https://www.ncbi.nlm.nih.gov/pubmed/33994864
http://dx.doi.org/10.7150/ijbs.55919