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Cis-acting: A pattern of lncRNAs for gene regulation in induced pluripotent stem cells from patients with Down syndrome determined by integrative analysis of lncRNA and mRNA profiling data

Down syndrome (DS), caused by the trisomy of chromosome 21, is one of the common chromosomal disorders, the main clinical manifestations of which are delayed nervous development and intellectual disability. Long non-coding RNAs (lncRNAs) have critical roles in various biological processes, including...

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Detalles Bibliográficos
Autores principales: Ma, Wenbo, Liu, Yanna, Ma, Houshi, Ren, Zhaorui, Yan, Jingbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120638/
https://www.ncbi.nlm.nih.gov/pubmed/34007310
http://dx.doi.org/10.3892/etm.2021.10133