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Exogenous BMP9 promotes lung fibroblast HFL-1 cell activation via ALK1/Smad1/5 signaling in vitro

Bone morphogenetic protein 9 (BMP9) has recently been described as a crucial regulator in modulating fibroblast-type cell activation. Activin receptor-like kinase 1 (ALK1) is a high affinity receptor for BMP9 that exerts its role via Smad1/5. However, the functional roles of BMP9 in activating lung...

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Detalles Bibliográficos
Autores principales: Wang, Yaqun, Sima, Xiaonan, Ying, Ying, Huang, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120641/
https://www.ncbi.nlm.nih.gov/pubmed/34007337
http://dx.doi.org/10.3892/etm.2021.10160