Unconventional endocytosis and trafficking of transferrin receptor induced by iron

The posttranslational regulation of transferrin receptor (TfR1) is largely unknown. We investigated whether iron availability affects TfR1 endocytic cycle and protein stability in HepG2 hepatoma cells exposed to ferric ammonium citrate (FAC). NH(4)Cl and bafilomycin A1, but not the proteasomal inhib...

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Detalles Bibliográficos
Autores principales: Gammella, Elena, Lomoriello, Irene Schiano, Conte, Alexia, Freddi, Stefano, Alberghini, Alessandra, Poli, Maura, Sigismund, Sara, Cairo, Gaetano, Recalcati, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120689/
https://www.ncbi.nlm.nih.gov/pubmed/33236955
http://dx.doi.org/10.1091/mbc.E20-02-0129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120689/
https://www.ncbi.nlm.nih.gov/pubmed/33236955
http://dx.doi.org/10.1091/mbc.E20-02-0129

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