Whole-genome screen identifies diverse pathways that negatively regulate ciliogenesis

We performed a high-throughput whole-genome RNAi screen to identify novel inhibitors of ciliogenesis in normal and basal breast cancer cells. Our screen uncovered a previously undisclosed, extensive network of genes linking integrin signaling and cellular adhesion to the extracellular matrix (ECM) w...

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Detalles Bibliográficos
Autores principales: Failler, Marion, Giro-Perafita, Ariadna, Owa, Mikito, Srivastava, Shalini, Yun, Chi, Kahler, David J., Unutmaz, Derya, Esteva, Francisco J., Sánchez, Irma, Dynlacht, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120696/
https://www.ncbi.nlm.nih.gov/pubmed/33206585
http://dx.doi.org/10.1091/mbc.E20-02-0111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120696/
https://www.ncbi.nlm.nih.gov/pubmed/33206585
http://dx.doi.org/10.1091/mbc.E20-02-0111

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