Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-κB pathways

BACKGROUND: To investigate the role and regulatory mechanisms of fargesin, one of the main components of Magnolia fargesii, in macrophage reprogramming and crosstalk across cartilage and synovium during osteoarthritis (OA) development. METHODS: Ten-week-old male C57BL/6 mice were randomized and assi...

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Detalles Bibliográficos
Autores principales: Lu, Jiansen, Zhang, Hongbo, Pan, Jianying, Hu, Zhiqiang, Liu, Liangliang, Liu, Yanli, Yu, Xiao, Bai, Xiaochun, Cai, Daozhang, Zhang, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120707/
https://www.ncbi.nlm.nih.gov/pubmed/33990219
http://dx.doi.org/10.1186/s13075-021-02512-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120707/
https://www.ncbi.nlm.nih.gov/pubmed/33990219
http://dx.doi.org/10.1186/s13075-021-02512-z

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