METTL13 inhibits progression of clear cell renal cell carcinoma with repression on PI3K/AKT/mTOR/HIF-1α pathway and c-Myc expression

BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is the most common and aggressive type of renal malignancy. Methyltransferase like 13 (METTL13) functions as an oncogene in most of human cancers, but its function and mechanism in ccRCC remains unreported. METHODS: qRT-PCR, western blotting and im...

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Detalles Bibliográficos
Autores principales: Liu, Zhuonan, Sun, Tianshui, Piao, Chiyuan, Zhang, Zhe, Kong, Chuize
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120818/
https://www.ncbi.nlm.nih.gov/pubmed/33985542
http://dx.doi.org/10.1186/s12967-021-02879-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120818/
https://www.ncbi.nlm.nih.gov/pubmed/33985542
http://dx.doi.org/10.1186/s12967-021-02879-2

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