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Combining transposon mutagenesis and reporter genes to identify novel regulators of the topA promoter in Streptomyces
BACKGROUND: Identifying the regulatory factors that control transcriptional activity is a major challenge of gene expression studies. Here, we describe the application of a novel approach for in vivo identification of regulatory proteins that may directly or indirectly control the transcription of a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120823/ https://www.ncbi.nlm.nih.gov/pubmed/33985526 http://dx.doi.org/10.1186/s12934-021-01590-7 |