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HCMB: A stable and efficient algorithm for processing the normalization of highly sparse Hi-C contact data
The high-throughput genome-wide chromosome conformation capture (Hi-C) method has recently become an important tool to study chromosomal interactions where one can extract meaningful biological information including P(s) curve, topologically associated domains, A/B compartments, and other biological...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120939/ https://www.ncbi.nlm.nih.gov/pubmed/34025950 http://dx.doi.org/10.1016/j.csbj.2021.04.064 |