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HCMB: A stable and efficient algorithm for processing the normalization of highly sparse Hi-C contact data

The high-throughput genome-wide chromosome conformation capture (Hi-C) method has recently become an important tool to study chromosomal interactions where one can extract meaningful biological information including P(s) curve, topologically associated domains, A/B compartments, and other biological...

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Detalles Bibliográficos
Autores principales: Wu, Honglong, Wang, Xuebin, Chu, Mengtian, Li, Dongfang, Cheng, Lixin, Zhou, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120939/
https://www.ncbi.nlm.nih.gov/pubmed/34025950
http://dx.doi.org/10.1016/j.csbj.2021.04.064