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Retracing our steps to understand ketamine in depression: A focused review of hypothesized mechanisms of action
INTRODUCTION: MDD represents a significant burden worldwide, and while a number of approved treatments exist, there are high rates of treatment resistance and refractoriness. Ketamine, an N-methyl-d-aspartate receptor (NMDAR) antagonist, is a novel, rapid-acting antidepressant, however the mechanism...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
College of Psychiatric & Neurologic Pharmacists
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8120982/ https://www.ncbi.nlm.nih.gov/pubmed/34026396 http://dx.doi.org/10.9740/mhc.2021.05.200 |