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Boosting Akt Pathway by Rupatadine Modulates Th17/Tregs Balance for Attenuation of Isoproterenol-Induced Heart Failure in Rats

Disruption of Th17/Tregs homeostasis plays a crucial role in governing the immune response during myocardial fibrosis and its progression to heart failure. The present study aimed to assess for the first time the possible protection afforded by rupatadine against isoproterenol-induced heart failure...

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Detalles Bibliográficos
Autores principales: Ahmed, Lamiaa A., Mohamed, Ahmed F., Abd El-Haleim, Enas A., El-Tanbouly, Dalia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121023/
https://www.ncbi.nlm.nih.gov/pubmed/33995066
http://dx.doi.org/10.3389/fphar.2021.651150