Cargando…
Boosting Akt Pathway by Rupatadine Modulates Th17/Tregs Balance for Attenuation of Isoproterenol-Induced Heart Failure in Rats
Disruption of Th17/Tregs homeostasis plays a crucial role in governing the immune response during myocardial fibrosis and its progression to heart failure. The present study aimed to assess for the first time the possible protection afforded by rupatadine against isoproterenol-induced heart failure...
Autores principales: | Ahmed, Lamiaa A., Mohamed, Ahmed F., Abd El-Haleim, Enas A., El-Tanbouly, Dalia M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121023/ https://www.ncbi.nlm.nih.gov/pubmed/33995066 http://dx.doi.org/10.3389/fphar.2021.651150 |
Ejemplares similares
-
Paeonol Attenuated Vascular Fibrosis Through Regulating Treg/Th17 Balance in a Gut Microbiota-Dependent Manner
por: Shi, Xiaoyan, et al.
Publicado: (2021) -
Rupatadine
por: Kaur, Manpreet, et al.
Publicado: (2013) -
Bufei Yishen Formula Restores Th17/Treg Balance and Attenuates Chronic Obstructive Pulmonary Disease via Activation of the Adenosine 2a Receptor
por: Zhao, Peng, et al.
Publicado: (2020) -
Aloperine Ameliorates IMQ-Induced Psoriasis by Attenuating Th17 Differentiation and Facilitating Their Conversion to Treg
por: Zhou, Hai-Feng, et al.
Publicado: (2022) -
Ciprofol attenuates the isoproterenol-induced oxidative damage, inflammatory response and cardiomyocyte apoptosis
por: Yang, Yunzhao, et al.
Publicado: (2022)