The formin inhibitor SMIFH2 inhibits members of the myosin superfamily

The small molecular inhibitor of formin FH2 domains, SMIFH2, is widely used in cell biological studies. It inhibits formin-driven actin polymerization in vitro, but not polymerization of pure actin. It is active against several types of formin from different species. Here, we found that SMIFH2 inhib...

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Detalles Bibliográficos
Autores principales: Nishimura, Yukako, Shi, Shidong, Zhang, Fang, Liu, Rong, Takagi, Yasuharu, Bershadsky, Alexander D., Viasnoff, Virgile, Sellers, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121067/
https://www.ncbi.nlm.nih.gov/pubmed/33589498
http://dx.doi.org/10.1242/jcs.253708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121067/
https://www.ncbi.nlm.nih.gov/pubmed/33589498
http://dx.doi.org/10.1242/jcs.253708

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