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The formin inhibitor SMIFH2 inhibits members of the myosin superfamily
The small molecular inhibitor of formin FH2 domains, SMIFH2, is widely used in cell biological studies. It inhibits formin-driven actin polymerization in vitro, but not polymerization of pure actin. It is active against several types of formin from different species. Here, we found that SMIFH2 inhib...
Autores principales: | Nishimura, Yukako, Shi, Shidong, Zhang, Fang, Liu, Rong, Takagi, Yasuharu, Bershadsky, Alexander D., Viasnoff, Virgile, Sellers, James R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121067/ https://www.ncbi.nlm.nih.gov/pubmed/33589498 http://dx.doi.org/10.1242/jcs.253708 |
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