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PolyQ length co-evolution in neural proteins

Intermolecular co-evolution optimizes physiological performance in functionally related proteins, ultimately increasing molecular co-adaptation and evolutionary fitness. Polyglutamine (polyQ) repeats, which are over-represented in nervous system-related proteins, are increasingly recognized as lengt...

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Detalles Bibliográficos
Autores principales: Vaglietti, Serena, Fiumara, Ferdinando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121095/
https://www.ncbi.nlm.nih.gov/pubmed/34017944
http://dx.doi.org/10.1093/nargab/lqab032