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PHF20 inhibition promotes apoptosis and cisplatin chemosensitivity via the OCT4-p-STAT3-MCL1 signaling pathway in hypopharyngeal squamous cell carcinoma

Cisplatin is a widely used platinum-based chemotherapeutic agent for hypopharyngeal squamous cell carcinoma (HSCC). However, resistance to cisplatin limits its use for the treatment of HSCC, and the underlying molecular mechanism requires further investigation. The present study performed functional...

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Detalles Bibliográficos
Autores principales: Liu, Xiuxiu, Zhang, Zhancheng, Kan, Shifeng, Lv, Zhenghua, Zhou, Shengli, Liu, Xianfang, Jing, Peihang, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121096/
https://www.ncbi.nlm.nih.gov/pubmed/33982773
http://dx.doi.org/10.3892/ijo.2021.5218