Phenotypic Differences between the Alzheimer’s Disease-Related hAPP-J20 Model and Heterozygous Zbtb20 Knock-Out Mice

Diverse gene products contribute to the pathogenesis of Alzheimer’s disease (AD). Experimental models have helped elucidate their mechanisms and impact on brain functions. Human amyloid precursor protein (hAPP) transgenic mice from line J20 (hAPP-J20 mice) are widely used to simulate key aspects of...

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Detalles Bibliográficos
Autores principales: Gulbranson, Daniel R., Ho, Kaitlyn, Yu, Gui-Qiu, Yu, Xinxing, Das, Melanie, Shao, Eric, Kim, Daniel, Zhang, Weiping J., Choudhary, Krishna, Thomas, Reuben, Mucke, Lennart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121260/
https://www.ncbi.nlm.nih.gov/pubmed/33833046
http://dx.doi.org/10.1523/ENEURO.0089-21.2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121260/
https://www.ncbi.nlm.nih.gov/pubmed/33833046
http://dx.doi.org/10.1523/ENEURO.0089-21.2021

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