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Evaluation of polygenic prediction methodology within a reference-standardized framework

The predictive utility of polygenic scores is increasing, and many polygenic scoring methods are available, but it is unclear which method performs best. This study evaluates the predictive utility of polygenic scoring methods within a reference-standardized framework, which uses a common set of var...

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Detalles Bibliográficos
Autores principales: Pain, Oliver, Glanville, Kylie P., Hagenaars, Saskia P., Selzam, Saskia, Fürtjes, Anna E., Gaspar, Héléna A., Coleman, Jonathan R. I., Rimfeld, Kaili, Breen, Gerome, Plomin, Robert, Folkersen, Lasse, Lewis, Cathryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121285/
https://www.ncbi.nlm.nih.gov/pubmed/33945532
http://dx.doi.org/10.1371/journal.pgen.1009021