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Copy number signature analysis tool and its application in prostate cancer reveals distinct mutational processes and clinical outcomes
Genome alteration signatures reflect recurring patterns caused by distinct endogenous or exogenous mutational events during the evolution of cancer. Signatures of single base substitution (SBS) have been extensively studied in different types of cancer. Copy number alterations are important drivers...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121287/ https://www.ncbi.nlm.nih.gov/pubmed/33945534 http://dx.doi.org/10.1371/journal.pgen.1009557 |