Cargando…

Copy number signature analysis tool and its application in prostate cancer reveals distinct mutational processes and clinical outcomes

Genome alteration signatures reflect recurring patterns caused by distinct endogenous or exogenous mutational events during the evolution of cancer. Signatures of single base substitution (SBS) have been extensively studied in different types of cancer. Copy number alterations are important drivers...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Shixiang, Li, Huimin, Song, Minfang, Tao, Ziyu, Wu, Tao, He, Zaoke, Zhao, Xiangyu, Wu, Kai, Liu, Xue-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121287/
https://www.ncbi.nlm.nih.gov/pubmed/33945534
http://dx.doi.org/10.1371/journal.pgen.1009557