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CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer

The CBFB gene is frequently mutated in several types of solid tumors. Emerging evidence suggests that CBFB is a tumor suppressor in breast cancer. However, our understanding of the tumor suppressive function of CBFB remains incomplete. Here, we analyze genetic interactions between mutations of CBFB...

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Detalles Bibliográficos
Autores principales: Malik, Navdeep, Yan, Hualong, Yang, Howard H., Ayaz, Gamze, DuBois, Wendy, Tseng, Yu-Chou, Kim, Young-Im, Jiang, Shunlin, Liu, Chengyu, Lee, Maxwell, Huang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121313/
https://www.ncbi.nlm.nih.gov/pubmed/33945523
http://dx.doi.org/10.1371/journal.pgen.1009553