Adipose triglyceride lipase protects renal cell endocytosis in a Drosophila dietary model of chronic kidney disease

Obesity-related renal lipotoxicity and chronic kidney disease (CKD) are prevalent pathologies with complex aetiologies. One hallmark of renal lipotoxicity is the ectopic accumulation of lipid droplets in kidney podocytes and in proximal tubule cells. Renal lipid droplets are observed in human CKD pa...

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Detalles Bibliográficos
Autores principales: Lubojemska, Aleksandra, Stefana, M. Irina, Sorge, Sebastian, Bailey, Andrew P., Lampe, Lena, Yoshimura, Azumi, Burrell, Alana, Collinson, Lucy, Gould, Alex P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121332/
https://www.ncbi.nlm.nih.gov/pubmed/33945525
http://dx.doi.org/10.1371/journal.pbio.3001230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121332/
https://www.ncbi.nlm.nih.gov/pubmed/33945525
http://dx.doi.org/10.1371/journal.pbio.3001230

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