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The bone is the major source of high circulating intact fibroblast growth factor-23 in acute murine polymicrobial sepsis induced by cecum ligation puncture

Fibroblast growth factor-23 (FGF23), a bone-produced hormone, plays a critical role in mineral homeostasis. Human diseases associated with excessive intact circulating FGF23 (iFGF23) result in hypophosphatemia and low vitamin D hormone in patients with normal kidney function. In addition, there is a...

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Detalles Bibliográficos
Autores principales: Bayer, Jessica, Vaghela, Ravikumar, Drechsler, Susanne, Osuchowski, Marcin F., Erben, Reinhold G., Andrukhova, Olena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121358/
https://www.ncbi.nlm.nih.gov/pubmed/33989306
http://dx.doi.org/10.1371/journal.pone.0251317