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Insights into the molecular mechanism of amyloid filament formation: Segmental folding of α-synuclein on lipid membranes

Recent advances in the structural biology of disease-relevant α-synuclein fibrils have revealed a variety of structures, yet little is known about the process of fibril aggregate formation. Characterization of intermediate species that form during aggregation is crucial; however, this has proven ver...

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Detalles Bibliográficos
Autores principales: Antonschmidt, Leif, Dervişoğlu, Rıza, Sant, Vrinda, Tekwani Movellan, Kumar, Mey, Ingo, Riedel, Dietmar, Steinem, Claudia, Becker, Stefan, Andreas, Loren B., Griesinger, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121418/
https://www.ncbi.nlm.nih.gov/pubmed/33990334
http://dx.doi.org/10.1126/sciadv.abg2174