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Insights into the molecular mechanism of amyloid filament formation: Segmental folding of α-synuclein on lipid membranes
Recent advances in the structural biology of disease-relevant α-synuclein fibrils have revealed a variety of structures, yet little is known about the process of fibril aggregate formation. Characterization of intermediate species that form during aggregation is crucial; however, this has proven ver...
Autores principales: | Antonschmidt, Leif, Dervişoğlu, Rıza, Sant, Vrinda, Tekwani Movellan, Kumar, Mey, Ingo, Riedel, Dietmar, Steinem, Claudia, Becker, Stefan, Andreas, Loren B., Griesinger, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121418/ https://www.ncbi.nlm.nih.gov/pubmed/33990334 http://dx.doi.org/10.1126/sciadv.abg2174 |
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