A framework for highly multiplexed dextramer mapping and prediction of T cell receptor sequences to antigen specificity

T cell receptor (TCR) antigen–specific recognition is essential for the adaptive immune system. However, building a TCR-antigen interaction map has been challenging due to the staggering diversity of TCRs and antigens. Accordingly, highly multiplexed dextramer-TCR binding assays have been recently d...

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Detalles Bibliográficos
Autores principales: Zhang, Wen, Hawkins, Peter G., He, Jing, Gupta, Namita T., Liu, Jinrui, Choonoo, Gabrielle, Jeong, Se W., Chen, Calvin R., Dhanik, Ankur, Dillon, Myles, Deering, Raquel, Macdonald, Lynn E., Thurston, Gavin, Atwal, Gurinder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121425/
https://www.ncbi.nlm.nih.gov/pubmed/33990328
http://dx.doi.org/10.1126/sciadv.abf5835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121425/
https://www.ncbi.nlm.nih.gov/pubmed/33990328
http://dx.doi.org/10.1126/sciadv.abf5835

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