The cGAS-STING pathway: The role of self-DNA sensing in inflammatory lung disease

The presence of DNA in the cytosol is usually a sign of microbial infections, which alerts the host innate immune system to mount a defense response. Cyclic GMP-AMP synthase (cGAS) is a critical cytosolic DNA sensor that elicits robust innate immune responses through the production of the second mes...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Ruihua, Ortiz Serrano, Tatiana P., Davis, Jennifer, Prigge, Andrew D., Ridge, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121456/
https://www.ncbi.nlm.nih.gov/pubmed/32860267
http://dx.doi.org/10.1096/fj.202001607R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121456/
https://www.ncbi.nlm.nih.gov/pubmed/32860267
http://dx.doi.org/10.1096/fj.202001607R

Ejemplares similares