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The cGAS-STING pathway: The role of self-DNA sensing in inflammatory lung disease

The presence of DNA in the cytosol is usually a sign of microbial infections, which alerts the host innate immune system to mount a defense response. Cyclic GMP-AMP synthase (cGAS) is a critical cytosolic DNA sensor that elicits robust innate immune responses through the production of the second mes...

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Detalles Bibliográficos
Autores principales:	Ma, Ruihua, Ortiz Serrano, Tatiana P., Davis, Jennifer, Prigge, Andrew D., Ridge, Karen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121456/ https://www.ncbi.nlm.nih.gov/pubmed/32860267 http://dx.doi.org/10.1096/fj.202001607R

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