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Tissue-resident-like CD4(+) T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung

T cell immunity is essential for the control of tuberculosis (TB), an important disease of the lung, and is generally studied in humans using peripheral blood cells. Mounting evidence, however, indicates that tissue-resident memory T cells (Trms) are superior at controlling many pathogens, including...

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Detalles Bibliográficos
Autores principales: Ogongo, Paul, Tezera, Liku B., Ardain, Amanda, Nhamoyebonde, Shepherd, Ramsuran, Duran, Singh, Alveera, Ng’oepe, Abigail, Karim, Farina, Naidoo, Taryn, Khan, Khadija, Dullabh, Kaylesh J., Fehlings, Michael, Lee, Boon Heng, Nardin, Alessandra, Lindestam Arlehamn, Cecilia S., Sette, Alessandro, Behar, Samuel M., Steyn, Adrie J.C., Madansein, Rajhmun, Kløverpris, Henrik N., Elkington, Paul T., Leslie, Alasdair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121523/
https://www.ncbi.nlm.nih.gov/pubmed/33848273
http://dx.doi.org/10.1172/JCI142014