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Tissue-resident-like CD4(+) T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung
T cell immunity is essential for the control of tuberculosis (TB), an important disease of the lung, and is generally studied in humans using peripheral blood cells. Mounting evidence, however, indicates that tissue-resident memory T cells (Trms) are superior at controlling many pathogens, including...
Autores principales: | Ogongo, Paul, Tezera, Liku B., Ardain, Amanda, Nhamoyebonde, Shepherd, Ramsuran, Duran, Singh, Alveera, Ng’oepe, Abigail, Karim, Farina, Naidoo, Taryn, Khan, Khadija, Dullabh, Kaylesh J., Fehlings, Michael, Lee, Boon Heng, Nardin, Alessandra, Lindestam Arlehamn, Cecilia S., Sette, Alessandro, Behar, Samuel M., Steyn, Adrie J.C., Madansein, Rajhmun, Kløverpris, Henrik N., Elkington, Paul T., Leslie, Alasdair |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121523/ https://www.ncbi.nlm.nih.gov/pubmed/33848273 http://dx.doi.org/10.1172/JCI142014 |
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