Thymosin β4 protects against aortic aneurysm via endocytic regulation of growth factor signaling

Vascular stability and tone are maintained by contractile smooth muscle cells (VSMCs). However, injury-induced growth factors stimulate a contractile-synthetic phenotypic modulation which increases susceptibility to abdominal aortic aneurysm (AAA). As a regulator of embryonic VSMC differentiation, w...

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Detalles Bibliográficos
Autores principales: Munshaw, Sonali, Bruche, Susann, Redpath, Andia N., Jones, Alisha, Patel, Jyoti, Dubé, Karina N., Lee, Regent, Hester, Svenja S., Davies, Rachel, Neal, Giles, Handa, Ashok, Sattler, Michael, Fischer, Roman, Channon, Keith M., Smart, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121525/
https://www.ncbi.nlm.nih.gov/pubmed/33784254
http://dx.doi.org/10.1172/JCI127884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121525/
https://www.ncbi.nlm.nih.gov/pubmed/33784254
http://dx.doi.org/10.1172/JCI127884

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