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GABA(B) receptor auxiliary subunits modulate Cav2.3-mediated release from medial habenula terminals

The synaptic connection from medial habenula (MHb) to interpeduncular nucleus (IPN) is critical for emotion-related behaviors and uniquely expresses R-type Ca(2+) channels (Cav2.3) and auxiliary GABA(B) receptor (GBR) subunits, the K(+)-channel tetramerization domain-containing proteins (KCTDs). Act...

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Detalles Bibliográficos
Autores principales: Bhandari, Pradeep, Vandael, David, Fernández-Fernández, Diego, Fritzius, Thorsten, Kleindienst, David, Önal, Cihan, Montanaro, Jacqueline, Gassmann, Martin, Jonas, Peter, Kulik, Akos, Bettler, Bernhard, Shigemoto, Ryuichi, Koppensteiner, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121548/
https://www.ncbi.nlm.nih.gov/pubmed/33913808
http://dx.doi.org/10.7554/eLife.68274