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Isoquercitrin protects HUVECs against high glucose-induced apoptosis through regulating p53 proteasomal degradation

High glucose (HG)-induced endothelial apoptosis serves an important role in the vascular dysfunction associated with diabetes mellitus (DM). It has been reported that isoquercitrin (IQC), a flavonoid glucoside, possesses an anti-DM effect, but the mechanism requires further investigation. The presen...

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Detalles Bibliográficos
Autores principales: Liu, Libo, Huang, Sihui, Xu, Man, Gong, Yan, Li, Dan, Wan, Chunxia, Wu, Haiming, Tang, Qizhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121554/
https://www.ncbi.nlm.nih.gov/pubmed/33982778
http://dx.doi.org/10.3892/ijmm.2021.4955