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Myocardin-related transcription factor A nuclear translocation contributes to mechanical overload-induced nucleus pulposus fibrosis in rats with intervertebral disc degeneration

Previous studies have reported that the Ras homolog family member A (RhoA)/myocardin-related transcription factor A (MRTF-A) nuclear translocation axis positively regulates fibrogenesis induced by mechanical forces in various organ systems. The aim of the present study was to determine whether this...

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Detalles Bibliográficos
Autores principales: Kong, Meng, Zhang, Yiran, Song, Mengxiong, Cong, Wenbin, Gao, Changtong, Zhang, Jiajun, Han, Shuo, Tu, Qihao, Ma, Xuexiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121555/
https://www.ncbi.nlm.nih.gov/pubmed/33982787
http://dx.doi.org/10.3892/ijmm.2021.4956