Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments

Defining the principles of T cell migration in structurally and mechanically complex tumor microenvironments is critical to understanding escape from antitumor immunity and optimizing T cell-related therapeutic strategies. Here, we engineered nanotextured elastic platforms to study and enhance T cel...

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Detalles Bibliográficos
Autores principales: Tabdanov, Erdem D., Rodríguez-Merced, Nelson J., Cartagena-Rivera, Alexander X., Puram, Vikram V., Callaway, Mackenzie K., Ensminger, Ethan A., Pomeroy, Emily J., Yamamoto, Kenta, Lahr, Walker S., Webber, Beau R., Moriarity, Branden S., Zhovmer, Alexander S., Provenzano, Paolo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121808/
https://www.ncbi.nlm.nih.gov/pubmed/33990566
http://dx.doi.org/10.1038/s41467-021-22985-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121808/
https://www.ncbi.nlm.nih.gov/pubmed/33990566
http://dx.doi.org/10.1038/s41467-021-22985-5

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