Cargando…

Loss of the WNT9a ligand aggravates the rheumatoid arthritis-like symptoms in hTNF transgenic mice

Agonists and antagonists of the canonical Wnt signaling pathway are modulators of pathological aspects of rheumatoid arthritis (RA). Their activity is primarily modifying bone loss and bone formation, as shown in animal models of RA. More recently, modulation of Wnt signaling by the antagonist Scler...

Descripción completa

Detalles Bibliográficos
Autores principales: Teufel, Stefan, Köckemann, Petra, Fabritius, Christine, Wolff, Lena I., Bertrand, Jessica, Pap, Thomas, Hartmann, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121832/
https://www.ncbi.nlm.nih.gov/pubmed/33990546
http://dx.doi.org/10.1038/s41419-021-03786-6