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Loss of the WNT9a ligand aggravates the rheumatoid arthritis-like symptoms in hTNF transgenic mice
Agonists and antagonists of the canonical Wnt signaling pathway are modulators of pathological aspects of rheumatoid arthritis (RA). Their activity is primarily modifying bone loss and bone formation, as shown in animal models of RA. More recently, modulation of Wnt signaling by the antagonist Scler...
Autores principales: | Teufel, Stefan, Köckemann, Petra, Fabritius, Christine, Wolff, Lena I., Bertrand, Jessica, Pap, Thomas, Hartmann, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121832/ https://www.ncbi.nlm.nih.gov/pubmed/33990546 http://dx.doi.org/10.1038/s41419-021-03786-6 |
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