Cephalomannine inhibits hypoxia-induced cellular function via the suppression of APEX1/HIF-1α interaction in lung cancer

Lung cancer (LC) is one of the leading causes of cancer-related death. As one of the key features of tumor microenvironment, hypoxia conditions are associated with poor prognosis in LC patients. Upregulation of hypoxic-induced factor-1α (HIF-1α) leads to the activation of various factors that contri...

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Detalles Bibliográficos
Autores principales: Ullah, Asmat, Leong, Sze Wei, Wang, Jingjing, Wu, Qing, Ghauri, Mohsin Ahmad, Sarwar, Ammar, Su, Qi, Zhang, Yanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121842/
https://www.ncbi.nlm.nih.gov/pubmed/33990544
http://dx.doi.org/10.1038/s41419-021-03771-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121842/
https://www.ncbi.nlm.nih.gov/pubmed/33990544
http://dx.doi.org/10.1038/s41419-021-03771-z

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