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PHC1 maintains pluripotency by organizing genome-wide chromatin interactions of the Nanog locus

Polycomb group (PcG) proteins maintain cell identity by repressing gene expression during development. Surprisingly, emerging studies have recently reported that a number of PcG proteins directly activate gene expression during cell fate determination process. However, the mechanisms by which they d...

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Detalles Bibliográficos
Autores principales: Chen, Li, Tong, Qiaoqiao, Chen, Xiaowen, Jiang, Penglei, Yu, Hua, Zhao, Qianbing, Sun, Lingang, Liu, Chao, Gu, Bin, Zheng, Yuping, Fei, Lijiang, Jiang, Xiao, Li, Wenjuan, Volpe, Giacomo, Abdul, Mazid MD., Guo, Guoji, Zhang, Jin, Qian, Pengxu, Sun, Qiming, Neculai, Dante, Esteban, Miguel A., Li, Chen, Wen, Feiqiu, Ji, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121881/
https://www.ncbi.nlm.nih.gov/pubmed/33990559
http://dx.doi.org/10.1038/s41467-021-22871-0