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Therapeutic potential of targeting membrane-spanning proteoglycan SDC4 in hepatocellular carcinoma
Syndecan-4 (SDC4) functions as a major endogenous membrane-associated receptor and widely regulates cytoskeleton, cell adhesion, and cell migration in human tumorigenesis and development, which represents a charming anti-cancer therapeutic target. Here, SDC4 was identified as a direct cellular targe...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121893/ https://www.ncbi.nlm.nih.gov/pubmed/33990545 http://dx.doi.org/10.1038/s41419-021-03780-y |