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Therapeutic potential of targeting membrane-spanning proteoglycan SDC4 in hepatocellular carcinoma

Syndecan-4 (SDC4) functions as a major endogenous membrane-associated receptor and widely regulates cytoskeleton, cell adhesion, and cell migration in human tumorigenesis and development, which represents a charming anti-cancer therapeutic target. Here, SDC4 was identified as a direct cellular targe...

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Detalles Bibliográficos
Autores principales: Yang, Heng, Liu, Yang, Zhao, Mei-Mei, Guo, Qiang, Zheng, Xi-Kang, Liu, Dan, Zeng, Ke-Wu, Tu, Peng-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121893/
https://www.ncbi.nlm.nih.gov/pubmed/33990545
http://dx.doi.org/10.1038/s41419-021-03780-y