Malfunctioning CD106-positive, short-term hematopoietic stem cells trigger diabetic neuropathy in mice by cell fusion

Diabetic neuropathy is an incurable disease. We previously identified a mechanism by which aberrant bone marrow-derived cells (BMDCs) pathologically expressing proinsulin/TNF-α fuse with residential neurons to impair neuronal function. Here, we show that CD106-positive cells represent a significant...

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Detalles Bibliográficos
Autores principales: Katagi, Miwako, Terashima, Tomoya, Ohashi, Natsuko, Nakae, Yuki, Yamada, Akane, Nakagawa, Takahiko, Miyazawa, Itsuko, Maegawa, Hiroshi, Okano, Junko, Suzuki, Yoshihisa, Fujino, Kazunori, Eguchi, Yutaka, Kojima, Hideto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121918/
https://www.ncbi.nlm.nih.gov/pubmed/33990693
http://dx.doi.org/10.1038/s42003-021-02082-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121918/
https://www.ncbi.nlm.nih.gov/pubmed/33990693
http://dx.doi.org/10.1038/s42003-021-02082-5

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