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Total genetic contribution assessment across the human genome

Quantifying the overall magnitude of every single locus’ genetic effect on the widely measured human phenome is of great challenge. We introduce a unified modelling technique that can consistently provide a total genetic contribution assessment (TGCA) of a gene or genetic variant without thresholdin...

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Detalles Bibliográficos
Autores principales: Li, Ting, Ning, Zheng, Yang, Zhijian, Zhai, Ranran, Zheng, Chenqing, Xu, Wenzheng, Wang, Yipeng, Ying, Kejun, Chen, Yiwen, Shen, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121943/
https://www.ncbi.nlm.nih.gov/pubmed/33990588
http://dx.doi.org/10.1038/s41467-021-23124-w