Context-specific action of macrolide antibiotics on the eukaryotic ribosome

Macrolide antibiotics bind in the nascent peptide exit tunnel of the bacterial ribosome and prevent polymerization of specific amino acid sequences, selectively inhibiting translation of a subset of proteins. Because preventing translation of individual proteins could be beneficial for the treatment...

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Detalles Bibliográficos
Autores principales: Svetlov, Maxim S., Koller, Timm O., Meydan, Sezen, Shankar, Vaishnavi, Klepacki, Dorota, Polacek, Norbert, Guydosh, Nicholas R., Vázquez-Laslop, Nora, Wilson, Daniel N., Mankin, Alexander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121947/
https://www.ncbi.nlm.nih.gov/pubmed/33990576
http://dx.doi.org/10.1038/s41467-021-23068-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121947/
https://www.ncbi.nlm.nih.gov/pubmed/33990576
http://dx.doi.org/10.1038/s41467-021-23068-1

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