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Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance
Chemotherapy remains the standard of care for most cancers worldwide, however development of chemoresistance due to the presence of the drug-effluxing ATP binding cassette (ABC) transporters remains a significant problem. The development of safe and effective means to overcome chemoresistance is cri...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121950/ https://www.ncbi.nlm.nih.gov/pubmed/33990571 http://dx.doi.org/10.1038/s41467-021-23071-6 |