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Modeling regulatory network topology improves genome-wide analyses of complex human traits

Genome-wide association studies (GWAS) have cataloged many significant associations between genetic variants and complex traits. However, most of these findings have unclear biological significance, because they often have small effects and occur in non-coding regions. Integration of GWAS with gene...

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Detalles Bibliográficos
Autores principales: Zhu, Xiang, Duren, Zhana, Wong, Wing Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121952/
https://www.ncbi.nlm.nih.gov/pubmed/33990562
http://dx.doi.org/10.1038/s41467-021-22588-0