High-throughput sequencing defines donor and recipient HLA B-cell epitope frequencies for prospective matching in transplantation

Compatibility for human leukocyte antigen (HLA) genes between transplant donors and recipients improves graft survival but prospective matching is rarely performed due to the vast heterogeneity of this gene complex. To reduce complexity, we have combined next-generation sequencing and in silico mapp...

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Detalles Bibliográficos
Autores principales: Tran, Jenny N., Günther, Oliver P., Sherwood, Karen R., Fenninger, Franz, Allan, Lenka L., Lan, James, Sapir-Pichhadze, Ruth, Duquesnoy, Rene, Claas, Frans, Marsh, Steven G. E., McMaster, W. Robert, Keown, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121953/
https://www.ncbi.nlm.nih.gov/pubmed/33990681
http://dx.doi.org/10.1038/s42003-021-01989-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121953/
https://www.ncbi.nlm.nih.gov/pubmed/33990681
http://dx.doi.org/10.1038/s42003-021-01989-3

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