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Recognition of acrolein-specific epitopes by B cell receptors triggers an innate immune response

Natural antibodies, predominantly immunoglobulin M (IgM), play an important role in the defense against pathogens and in maintaining homeostasis against oxidized molecules known as oxidation-specific epitopes, such as those contained in oxidized low-density lipoproteins. However, owing to the comple...

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Detalles Bibliográficos
Autores principales: Endo, Ryunosuke, Uchiyama, Kazuki, Lim, Sei-Young, Itakura, Masanori, Adachi, Takahiro, Uchida, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8121969/
https://www.ncbi.nlm.nih.gov/pubmed/33839149
http://dx.doi.org/10.1016/j.jbc.2021.100648