Defining intermediates and redundancies in coenzyme Q precursor biosynthesis

Coenzyme Q (CoQ), a redox-active lipid essential for oxidative phosphorylation, is synthesized by virtually all cells, but how eukaryotes make the universal CoQ head group precursor 4-hydroxybenzoate (4-HB) from tyrosine is unknown. The first and last steps of this pathway have been defined in Sacch...

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Detalles Bibliográficos
Autores principales: Robinson, Kyle P., Jochem, Adam, Johnson, Sheila E., Reddy, Thiruchelvi R., Russell, Jason D., Coon, Joshua J., Pagliarini, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122105/
https://www.ncbi.nlm.nih.gov/pubmed/33862086
http://dx.doi.org/10.1016/j.jbc.2021.100643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122105/
https://www.ncbi.nlm.nih.gov/pubmed/33862086
http://dx.doi.org/10.1016/j.jbc.2021.100643

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