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Factor Xa inhibitors: critical considerations for clinical development and testing

The selection of factor (F) X and its activated protease FXa for targeted inhibition to prevent and treat thrombotic conditions is based on an understanding of coagulation biochemistry, sequential steps that occur on tissue factor bearing cells and the interface of coagulation proteins, platelets, m...

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Detalles Bibliográficos
Autor principal: Becker, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122197/
https://www.ncbi.nlm.nih.gov/pubmed/33991266
http://dx.doi.org/10.1007/s11239-021-02455-x