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Mitochondrial ATP-Dependent Proteases—Biological Function and Potential Anti-Cancer Targets

SIMPLE SUMMARY: Alterations of cellular metabolism and bioenergetics, oxidative stress, and intracellular reactive oxygen species (ROS) levels are hallmarks of cancer development. Mitochondrial proteases, especially ATP-dependent proteases are essential to regulate mitochondrial function by maintain...

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Detalles Bibliográficos
Autores principales: Feng, Yue, Nouri, Kazem, Schimmer, Aaron D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122244/
https://www.ncbi.nlm.nih.gov/pubmed/33922062
http://dx.doi.org/10.3390/cancers13092020