Synthesis of New Triazolopyrazine Antimalarial Compounds

A radical approach to late-stage functionalization using photoredox and Diversinate(™) chemistry on the Open Source Malaria (OSM) triazolopyrazine scaffold (Series 4) resulted in the synthesis of 12 new analogues, which were characterized by NMR, UV, and MS data analysis. The structures of four tria...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnson, Daniel J. G., Jenkins, Ian D., Huxley, Cohan, Coster, Mark J., Lum, Kah Yean, White, Jonathan M., Avery, Vicky M., Davis, Rohan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122397/
https://www.ncbi.nlm.nih.gov/pubmed/33919319
http://dx.doi.org/10.3390/molecules26092421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8122397/
https://www.ncbi.nlm.nih.gov/pubmed/33919319
http://dx.doi.org/10.3390/molecules26092421

Ejemplares similares